Last year, I wrote about why platform AI and intelligent agents were the next chapter for healthcare – not chatbots, not one-off model hype, but a fundamental transformation in how work gets done.
This year, I’m more optimistic – and more impatient.
While the value is real, the application of AI is still flawed in too many places: pilots that don’t scale, “AI features” that create new work, and vendors that promise outcomes without owning accountability. The ambition is great, but it continues to fall short on operational impact and measurable results.
That gap between promise and reality can’t persist much longer – nor should it. The pressure is rising on leaders to move beyond experimentation and towards accountable execution. In my view, 2026 will be the year the industry shifts focus: from talking about AI to demanding outcomes from it.
So here are my five predictions for where AI in healthcare is headed in 2026 – and what I think leaders should do about each.
1. Agents will stop being a category – and become reliable automation that elevates humans
What to expect
The word “agent” is overloaded. In 2026, the winners will be the technology solutions that feel less like “autonomy theater” and more like dependable, auditable work completion – with humans elevated, not sidelined.
Takeaway
Stop framing agents as a category, and start thinking of automated workflows as infrastructure. The real win is shifting from demo-grade autonomy to systems that healthcare organizations can trust and depend on. That means reliability isn’t a feature — it’s the product. Design with clear guardrails, robust exception handling, and intuitive ways for humans to stay meaningfully in the loop. When your team feels in control, trust builds — and that’s what ultimately drives lasting adoption and compound leverage.
2. The point-solution explosion will trigger consolidation pressure (and CIO fatigue)
What to expect
We will keep seeing an explosion of narrow AI tools. And then we’ll see the hangover: integration sprawl, governance sprawl, training sprawl, measurement sprawl. Healthcare doesn’t have the bandwidth for 10,000 vendors, and neither do you.
Takeaway
Consider adopting a platform strategy: fewer vendors, deeper integration, broader coverage. “More” isn’t better – it’s fragmentation.
3. Pricing will shift toward usage + outcomes – and fixed-fee will keep breaking
What to expect
AI isn’t a static SaaS seat. It’s work and it’s elastic. The industry will continue moving toward usage- and outcomes-based partnerships and pricing, and vendors will struggle if they try to force flat-fee economics onto variable workload reality.
Takeaway
Leaders should demand alignment: pay for measurable results, and structure contracts so vendors win when you win.
4. Orchestration + monitoring will become non-negotiable
What to expect
As AI starts taking action across systems and handling sensitive data, orchestration and auditability become non negotiable. Leaders will demand clear visibility into what an agent can access, the exact scope of work it is allowed to do, and a complete record of what it did. That means traceability, immutable audit logs, policy based permissions, exception queues, and SLA monitoring, the observability layer for a digital workforce.
Takeaway
If you cannot audit it, you cannot scale it. Treat orchestration as the control plane and auditability as the proof, not optional add ons.
5. The CIO role shifts from “cost function” to “productivity inflection function”
What to expect
AI will force a redefinition of IT leadership: not just keeping systems running, but contributing to top-line growth and compounding productivity across the enterprise -- with strategic partnerships and AI-enabled product innovation, as well as governance, guardrails, vendor rationalization, and measurable outcomes.
Takeaway
The playbook becomes: fewer tools, more leverage, faster deployment, stronger governance, clearer ROI.
What won’t change
The pace of AI innovation will only accelerate. New models will emerge, benchmarks will be shattered, and the hype cycle will keep spinning. But in healthcare, the fundamentals remain the same: outcomes matter more than novelty. Trust beats flash. And integration — not isolated brilliance — is what drives scale.
In 2026, healthcare leaders won’t reward the loudest AI pitch or the most dazzling demo. They’ll reward what’s always mattered: systems that create clarity instead of confusion, elevate people instead of overwhelming them, and deliver measurable impact that compounds.
So if you’re building, build for the long game: enterprise trust, operational lift, and infrastructure that scales. That’s what endures — and that’s what creates real change.
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